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Prime™ Feminene® Female Support Formula

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Primary Benefits* of Prime™ Feminene® Female Support Formula

Feel like you again.

  • Helps to reduce hot flashes and night sweats associated with menopause
  • Helps alleviate mild symptoms commonly associated with menopause
  • Helps stabilize mood
  • May help maintain normal hormone balance
  • Helps counteract mild effects of PMS
  • Helps maintain optimal female health

Feel Like You Again

What makes Prime Feminene Female Support Formula Unique?

Menopause is a natural biological process, defined as the time when a woman has naturally ceased having menstrual periods for one year. Common symptoms associated with menopause are both emotional and physical. Emotional symptoms can include mood swings, difficulty sleeping, increased irritability, low energy and feelings of sadness. Physical symptoms are often pain during intercourse due to vaginal dryness, night sweats and hot flashes. Considering the average age of menopause in the United States is only 52 years old – while the age of onset varies and can occur anytime between 40 and 60 - these symptoms can be challenging for women still living a full and active life. In addition, prior to menopause, some women experience perimenopause, a time-period that can include many of the symptoms of menopause before menstruation actually stops.*

At an age when many women are still juggling a career, family, friends and commitments, dealing with the symptoms of menopause or perimenopause can leave women looking for some relief. Several scientific studies have demonstrated how select herbs, vitamins and minerals help to promote optimal female health especially during times of menopause or perimenopause, without the harmful side effects of unnatural alternatives.*

Premenstrual syndrome or PMS is another natural, biological process that women go through. It occurs for up to two weeks prior to menstruation, and has been associated with a deficiency or excess of hormones. Symptoms of PMS include increased levels of anger and stress, bloating, breast tenderness, abdominal discomfort, sadness, short-term fatigue, head discomfort, hostility, trouble sleeping, joint discomfort, mood swings, nervousness and tension. Needless to say, finding relief from PMS symptoms is also important to many women.*

Prime™ Feminene® Female Support Formula is a dietary supplement created to help reduce hot flashes and night sweats, as well as other mild symptoms commonly associated with menopause or perimenopause as well as PMS. It may help stabilize moods and keep hormones in balance during these challenging, yet natural, biological processes women go through.*

Specially formulated with select nutrients, Prime Feminene includes herbs like black cohosh, dong quai, soy extract, wild yam and chaste berry. It also provides select vitamins to help with mood and stress. Prime Feminine helps women keep their bodies in balance resulting in a more balanced life. When juggling so many things in life, the last thing women want is to have unbalanced hormones and mood swings to deal with as well.*

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

What makes Prime Feminene Female Support Formula Unique?

Product Classifications

Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)

Vegan - The product is made without ingredients produced by or derived from animals

Quality Standards - GMP Operations and Standardized Ingredients

Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity

Key Ingredients

Black Cohosh (Root Extract, 2.5% triterpene glycosides)
Black cohosh is a perennial, shrub-like plant, native to the eastern deciduous forests of North America. Traditionally, Black Cohosh was used to provide relief from menstrual cramps; it has also been used to help assist with hot flashes accompanying menopause and PMS. The precise mechanism of action is unknown; although, the triterpene glycosides are considered the active constituents along with the isoflavones, alkaloids and phenolic acids. Black Cohosh may have a similar effect as estrogen, which is the female hormone that regulates the menstrual cycle. Low estrogen levels are linked with the symptoms associated with menopause, and Black Cohosh may help alleviate mild symptoms of menopause.*

Soy Extract (Soy Isoflavones, 3%)
Soy isoflavones are found in soybeans in the form of phytoestrogens. Phytoestrogens are nonsteriodal compounds that possess estrogen-like biological activity, and come from plants. Soy isoflavones have weak estrogenic and anti-estrogenic effects. They have been found to bind to estrogen receptors, alpha and beta; although, they appear to bind better to the beta estrogen receptors. Soy isoflavones include three main isoflavones, which are the aglycones genistein, daidzein and glycitein. Soy may be linked to alleviating mild menopausal symptoms and beneficial in promoting bone health.*

Dong Quai (Root Extract, 1% ligustilide)
Dong quai has been used in traditional Chinese and Native American medicine for thousands of years. The plant is related to both parsley and celery; its health properties come from the root. Dong quai is often referred to as the female ginseng because of its homeostatic effects during menstruation. Its most common use is to manage mild cramps and pain during menstruation as well as to alleviate some of the mild symptoms of menopause such as hot flashes. The specific mechanism of action is unknown; although, the groups of coumarins, ferulic acid and ligustilide appear to be the active constituents of the dong quai root. The coumarins aid in promoting normal blood flow, while the ferulic acid and ligustilide promote normal muscle relaxation. Dong quai is not a replacement for estrogen (although, some studies have shown that it has a similar effect as isoflavones) nor does it have any hormone-like effects on the body.*

Wild Yam
Wild Yam is a member of the Dioscorea family, which also includes the potato. The family is named for Dioscorides, who was the first-century Greek physician whose botanical writings were the standard for more than one thousand years. The dried roots are the health-promoting part of the plant. Wild yam has been historically used for mild symptoms associated with menstruation and menopause, including cramping, hot flashes and occasional fatigue. It is native to North America, but the plant can be cultivated in tropical, subtropical and temperate regions all around the world. 

Chaste Berry Extract (Vitex agnus-castus)
Chaste berry extract or Vitex, is a shrub native to the Mediterranean and Central Asia, but can also be found around the United States. It is generally used in dietary supplements for promoting normal levels of female hormones and for mild symptoms of PMS and menopause. The flavonoids casticin, isovitexin and orientin are the main constituents of chaste berry extract. Because of its ability to support normal hormone balance, it is often used to promote a healthy menstrual cycle. PMS often occurs during the luteal phase of menstruation, thus maintaining hormone balance during this phase may help to counteract mild adverse effects of PMS.*

Horsetail (Equisetum arvense), also known as Peterwort, Dutch rushes, Shave-grass and Bottlebrush, is named from the bristly appearance of its jointed stems. The plant is found throughout the northern hemisphere, and only the stems exhibit beneficial health-related properties. It has the ability to draw excess water from the body, which makes it useful for cleansing the urinary tract. Horsetail is a natural source of silicon, iron and sodium, and also contains high amounts of calcium, chromium, crude fiber, magnesium, potassium, selenium and vitamin A. Horsetail is an excellent source of silicic acid, which contributes to its health benefits. Horsetail is commonly used to promote urinary tract health, but has also been shown to be helpful with mild symptoms of PMS and menopause.*

Red Clover
Red clover, like soy, contains high levels of isoflavones, which are well known for their subtle estrogen-like properties. Red clover has been shown in studies to help alleviate hot flashes associated with menopause. Red Clover is a small perennial herb with red or white flowers. It is native to Europe, central Asia, and northern Africa, but is also naturalized in many other parts of the world. Only the flowers are used in health supplements. It can be found as a dried herb, in tablets or capsules, and in alcohol solutions.*

Valerian Root
Valerian Root (Valerian officinalis) produces bright pink to white flowers, and grows 20 to 40 inches tall. It is native to Europe and temperate regions of Asia, and is cultivated in Europe, Japan and the United States. The Ancient Greek physician Galen referred to valerian as “Phu,” which is an expression of disgust at the plants smell. It was given the name all-heal in medieval times due to its natural healing properties. It is usually prepared as a tea, taken in capsule or tablet form, or used to make a bath additive. Valerian Root is commonly used to as a natural sleep aid, but is used for mild symptoms associated with premenstrual syndrome and menopause. 

Passiflora, also known as the passionflower, can be used to assist with occasional sleep difficulty and restlessness. Passiflora is a perennial vine, which reaches 30 feet in length. It grows naturally from the southeastern United States to Brazil and Argentina, and is cultivated as a garden plant in Europe. The blossoms are considered symbolic of Christ’s Passion, because the central corona represents the Crown of Thorns, which accounts for its name. The health value is found on the aboveground parts of the plants. Passiflora is available as an herb for tea, and is also an ingredient in some bath additives.*

Gamma linoleic acid (GLA) (lifesGLA)
Gamma linolenic acid (GLA) is an omega-6 fatty acid, derived from the seeds of plants such as evening primrose and borage. Deficiency of PGE1 (prostaglandin E1 (PGE1) has been linked with some of the symptoms associated with PMS. Additionally, some studies have shown that evening primrose oil helps counteract mild adverse effects of PMS.*

Thiamin HCl (Vitamin B1)
Thiamin plays an important role in carbohydrate metabolism and nerve function. Thiamin is required for a healthy nervous system and assists in the production of the neurotransmitter acetylcholine and gamma-aminobutyric acid (GABA). It is used in the manufacture of hydrochloric acid, and therefore plays a part in digestion, increases energy and helps promote mental clarity.*

Pantothenic Acid (Vitamin B5)
Pantothenic acid (vitamin B5) is a water-soluble vitamin involved in the Kreb’s cycle of energy production and promotes the normal production of the neurotransmitter acetylcholine. When the nerve impulse originating in the brain arrives at the nerve ending, it releases a chemical called acetylcholine, which promotes brain health. Pantothenic acid works together with vitamin B1, vitamin B2, and vitamin B3 to support the body’s normal production of adenosine triphosphate (ATP), the fuel our body uses to function. 

Pyridoxine HCl (Vitamin B6)
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. Vitamin B6 supports numerous metabolic pathways in the body. One specific function is that it supports the normal synthesis of neurotransmitters in the brain and peripheral nerve cells. 

Folic Acid
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans and peas are the best sources as well as Brewer’s yeast, which supplies additional B-vitamins. Folic acid boosts the benefits of vitamin B12 supplementation. Folic acid supports the normal utilization of amino acids and proteins. Scientific studies have found that when working in tandem with vitamin B12, folic acid supports healthy cardiovascular and nervous systems. 

Vitamin B12 (Methylcobalamin)
Methylcobalamin is one of the naturally-occurring forms of vitamin B12 found in the human body. The liver must convert cyanocobalamin, the form of B12 most commonly used in supplements, into methylcobalamin, before it can be properly utilized by the body; methylcobalamin is more effective than non-active forms of vitamin B12. Methylcobalamin also promotes the normal formation of SAMe (S-adenosylmethionine), a nutrient that positively impacts mood. 

Vitamin E (d-alpha-Tocopherol Succinate)
The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. Vitamin E is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical except the natural form of vitamin E is better absorbed and retained in the body. The natural form of alpha-tocopherol is known as "d-alpha tocopherol." The synthetic "dl-" form is the most common form found in dietary supplements. 


  1. What is Menopause?
    Menopause is the ceasing of the monthly female menstrual cycle. A woman is considered menopausal when she has been without a menstrual cycle for at least for one year. Common symptoms of menopause are emotional and physical changes, mood swings, sleeplessness, hot flashes and night sweats. Some women experience perimenopause prior to menopause, which is a time period that can include many of the symptoms of menopause before menstruation stops. The most common symptoms that perimenopausal and menopausal women complain of are hot flashes, flushes and sweats; thirty three percent of these women seek medical attention for the ailments.

  2. What are estrogens?
    Estrogens are a group of steroid compounds that are named for their importance in the estrus cycle. They function as the primary female sex hormone. Estrogen is present in men and women, but is usually at significantly higher levels in women of reproductive age. Estrogen is mainly produced in the developing follicles in the ovaries, but some is also produced by secondary sources such as the liver, adrenal glands and breasts. The secondary sources are particularly important for post-menopausal women. Estrogens function structurally to promote the formation of female secondary sex characteristics, stimulate endometrial growth, increase uterine growth, increasing vessel and skin maintenance and bone formation. 

  3. What causes menopause symptoms to occur?
    Menopause symptoms are caused by the loss of estrogen. However, not all menopause symptoms can be treated by estrogen.

  4. What is hormone replacement therapy?
    Hormone replacement therapy is a system of medical treatments for perimenopausal and postmenopausal women. It is based on the assumption that it may prevent discomfort and health problems caused by diminished estrogen hormones. Hormone replacement therapy involves a series of drugs designed to artificially boost hormone levels, using estrogens, progesterone or progestins, and sometimes testosterone. It is seen as a short-term relief from menopausal symptoms or as a longer-term treatment to reduce osteoporosis.

  5. When does Menopause occur?
    In the United States, 52 years old is the average age for menopause. However, the age of onset varies and can occur anytime between 40 and 60 years of age.

  6. What are some common non-hormonal supplements for menopause?
    The most common non-hormonal or herbal supplements for menopause are black cohosh, evening primrose oil, red clover, a vitamin B complex and vitamin E.*

  7. What is PMS?
    PMS, or premenstrual syndrome, has been associated with a deficiency or excess of hormones, stress, nutritional deficiencies and other nutritional or lifestyle factors. Symptoms that are commonly associated with PMS include increased levels of stress and weight. When does PMS occur? PMS occurs prior to menstruation for up to two weeks.

  8. How common is PMS?
    The percentage of women who experience PMS varies widely, but according to the American College of Obstetricians and Gynecologists, up to forty percent of menstruating women report some symptoms of PMS. For most women, the symptoms vary from mild to severe.

  9. Are there any foods that aggravate PMS symptoms?
    Yes. Some foods have been shown to aggravate the symptoms of PMS, such as saturated fats, hydrogenated fats, refined sugar, salt, caffeine and alcohol.

  10. How do I take Prime Feminene?
    As a dietary supplement for women in menopause, adults take two tablets or as directed by the healthcare provider.

  11. Are there any contraindications or warnings for Prime Feminene?
    Yes. If you are currently taking warfarin (Coumadin), or other antiplatelet/anticoagulant drugs, you should consult your healthcare provider before using this product. If you are currently taking any prescription medication or have an ongoing medical condition, or if you are pregnant or breastfeeding, consult your healthcare provider before using this product. If you are allergic to any of the ingredients listed, you should not take this product. 


  • Mayo, J. Black cohosh and chasteberry: herbs valued by women for centuries. Clinical Nutrition Insights. 6(15); 1-4, 1998.
  • Albertazzi P et al. The effect of dietary soy supplementation on hot flushes. Obstetrics and Gynecology. 91(1): 6-11, 1998. 
  • Albertazzi P et al. Dietary soy supplementation and phytoestrogen levels. Obstet Gynecol. 94:229-31, 1999.
  • Liske E et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizoma): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 11:163-74, 2002. 
  • Hardy, M. Herbs of special interest to women. Journal of the American Pharmaceutical Association. 40(2): 234-242, 2000.
  • Monograph. Angelica sinensis. Alternative Medicine Review. 9(4): 429-433, 2004.
  • Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997. 
  • Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999. 
  • Kurzer M. Hormonal effects of soy isoflavones: Studies in premenopausal and postmenopausal women. J Nutr. 130:660-1, 2000. 
  • Pino AM, Valladares LE, Palma MA, et al. Dietary isoflavones affect sex hormone-binding globulin levels in postmenopausal women. J Clin Endocrinol Metab. 85:2797-800, 2000. 
  • Duncan AM, Underhill KE, Xu X, et al. Modest hormonal effects of soy isoflavones in postmenopausal women. J Clin Endocrinol Metab. 84:3479-84, 1999.
  • Nicholls J, Lasley BL, Nakajima ST, et al. Effects of soy consumption on gonadotropin secretion and acute pituitary responses to gonadotropin-releasing hormone in women. J Nutr. 132:708-14, 2002. 
  • Mayo, J. Black cohosh and chasteberry: herbs valued by women for centuries. Clinical Nutrition Insights. 6(15); 1-4, 1998.
  • Cassidy, A., et al. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. American Journal of Clinical Nutrition. 60(3): 333-340, 1994. 
  • Hardy, M. Herbs of special interest to women. Journal of the American Pharmaceutical Association. 40(2): 234-242, 2000.


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by Anonymous

Bye bye hot flashes

In less than a week of taking this product there was a noticeable difference in my hot flashes. They were less intense. It’s been a life saver. I am thankful because I was suffering.

Response from Customer Service

Dear Valued Customer,

Thank you for sharing your experience with the Prime™ Feminene® Female Support Formula! We are thrilled to hear that it has made a positive changes to your overall wellbeing. We are committed to offering high-quality products that our customers find beneficial. Your feedback is truly valuable to us, and we appreciate you taking the time to let us know how our product has helped you. If you have any questions or need further assistance, please don't hesitate to reach out.

Thank you again,
The Product Information Team


by CaymeP

A must for women over 40!

In my mid 40’s I started waking up in the middle of the night with drenched, sweat-filled sheets. It made getting a good night’s sleep hard. After 2 days on this product, no more night sweats for me! It’s been a game changer.

Response from Customer Service

Dear Valued Customer,

Thank you so much for sharing your positive experience with our nutraMetrix Prime™ Feminene® Female Support Formula! We're delighted to hear that our product has made such a significant difference in your life, especially in improving your sleep quality. Your feedback is greatly appreciated and will undoubtedly help other women with similar experiences.

Thank you again!
The Product Information Team


by Anonymous

Great help for hormones!

This has been a great help to keep my hormones in balance and also helps my mood so that I don't have so many up's and down's.

Response from Customer Service

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Prime™ Feminene® Female Support Formula! We are so happy to hear you are pleased with the product!

Thank you again!
The Product Information Team


by CheleB

Feminene supports me through menopause

A customer, Jan, called frantic because she ran out of feminene She said this product is amazing. It absolutes supports me in finding relief from my hot flashes, irritability, and I can peacefully go about my day. I know exactly what she means which is why I won't go without it. Without Feminene-hot flashes. With Feminene-almost no hot flashes. So thankful for this supplement. I would recommend every woman try it. Chele Boe

Response from Customer Service

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Prime™ Feminene® Female Support Formula! We are so happy to hear you are pleased with the product!

Thank you again!
The Product Information Team



This product helps with hot flush

I have been taking this product for many years during my menopause. It helps with hot flush and mood swing.

Response from Customer Service

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Prime™ Feminene® Female Support Formula! We are happy to hear you are pleased with the product!

Thank you again!
The Product Information Team